XENICAL is an oral prescription diet pill medication which can help considerably overweight people to lose weight and keep it off. It contains the Active ingredient: Orlistat
Brand Name: Xenical®
Active Ingredient: orlistat
Dosage Form(s): Capsule
Company Name: Roche
Availability: Prescription only
FDA Approval Date: April 23, 1999
Xenical is one of a new class of anti-obesity drugs called lipase inhibitors.Lipase is the enzyme that breaks down fat for use by the body.Xenical interferes with lipase function, decreasing fat absorption by 30 percent. Xenical attaches itself to natural digestive enzymes and prevents them from breaking down fat. Since undigested fats are not absorbed, there is less calorie intake, which may have a positive effect on weight control.
The recommended dose is one 120-mg capsule by mouth with liquid at each main meal that contains fat. You should take XENICAL up to three times a day in conjunction with a reduced-calorie diet. Each time you take XENICAL, your nutritionally balanced meal should contain no more than about 30% of calories from fat.Take XENICAL during meals or up to 1 hour after a meal.
If you miss a dose of xenical, take it as soon as possible. But do not take 2 doses at once, doubling up of the medicine is a strict No!
If overdose is suspected, contact your local poison control center or emergency room immediately.
Store at room temperature (77 degrees F, 25 degrees C) away from light and moisture.
Duration of usage
Xenical is usually taken for 8 to 12 weeks. Weight loss begins within 2 weeks and continues for 6 to 12 months. The effect of using Xenical for more than 2 years is still unknown. But do remember that continuous use of a pill will not increase its benefits, as your body starts to build up a resistance to the effects of this medication after a few weeks of treatment. It is always advised to take help from the pill but not to get addicted to it. Use in combination with other appetite suppressants is generally not recommended. Consult your doctor before such use.
Side effects of Xenical are more common during the first year of treatment. More common side effects may include: Abdominal discomfort or pain , Anxiety , Arthritis , Back pain , Diarrhea , Dizziness , Earache , Fatigue , Fatty or oily stools ,Fecal urgency or incontinence , Flu , Gas with fecal discharge ,Gum problems ,Headache , Increased defecation ,Menstrual problems ,Muscle pain ,Nausea ,Oily discharge ,Rectal discomfort or pain ,Respiratory tract infections , Skin rash ,Sleep problems ,Tooth problems ,Urinary tract infections ,Vaginal inflammation and Vomiting. Less common side effects of xenical may include: Dry skin, Ear/Nose/Throat problems, joint disorders.If you notice other effects not listed above, contact your doctor, nurse or pharmacist.Side effects such as diarrhea and abdominal pain may be worse if you continue eating a high fat diet or even take a high-fat meal. Limit your fat intake .
- Dosage : Do not exceed the recommended dose or take this medicine for longer than prescribed without checking with your doctor. Exceeding the recommended dose or taking this medicine for longer than prescribed may cause serious Side Effects.
- Driving and Hazardous work : Xenical may cause dizziness or make you less alert than normal. Do not drive or do anything else that could be dangerous until you know how you react to Xenical
- Alcohol : Alcohol may increase unwanted side effects of dizziness, therefore, it is advisable to limit alcohol use while taking Xenical (or other appetite suppressants).
- Medical conditions : Tell your doctor your medical history, including: allergies, digestive disorders (malabsorption or cholestasis), low thyroid function (hypothyroidism), other metabolism problems (e.g., oxalate kidney stones, hyperoxaluria).
- Breast Feeding - Use of Xenical (or other appetite suppressants) while breast-feeding is NOT recommended; it may pass into breast milk, causing unwanted effects in nursing babies. Please consult your doctor for advice.
- Diet : This medicine can cause changes in your bowel habits, such as fatty or oily stools, due to the elimination of undigested fat in your stool. Xenical reduces the absorption of supplements of some fat soluble nutrients, particularly beta-carotene and vitamin E. You should therefore follow your doctor's advice in taking a well balanced diet rich in fruit and vegetables.
- Diabetics : If you are diabetic, Xenical may affect your blood sugar control. See your doctor regularly for monitoring and treatment adjustments.
- Some Drugs or medical conditions may interact with this medicine. Inform your Doctor or Pharmacist of all prescription and over-the-counter medicine that you are taking. If Xenical is taken with certain other drugs, the effects of either of the two could be increased, decreased or altered. It is especially important to check with your doctor before combining Xenical with the following:
- Cyclosporine (Neoral and Sandimmune)
- Pravastatin (Pravachol)
- Warfarin (Coumadin)
- Before taking orlistat, tell your doctor if you are taking any of the following medicines to lower cholesterol.You may require a dosage adjustment or special monitoring during treatment: atorvastatin (Lipitor),cerivastatin (Baycol),fluvastatin (Lescol),lovastatin (Mevacor),pravastatin (Pravachol), or simvastatin (Zocor).
- Orlistat may decrease your body's absorption of some fat-soluble vitamins. To ensure adequate nutrition, your doctor may recommend taking a multivitamin that contains vitamins D, E, K, and beta-carotene. Take your vitamin supplement once a day, at least 2 hours before or after a dose of orlistat.
- Xenical is not intended to be used in children or pregnant and nursing women.
- Inform your doctor of any other medical conditions, allergies, pregnancy or if you are breast-feeding.
- Do not share this medication with others. Follow your doctor-approved nutritional, reduced-calorie diet containing about 30 percent calories from fat. Also, exercise is recommended; however, first consult your doctor or pharmacist.
- The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional.
- It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.